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Cancer, Oncology & Supportive Care • ICD-10-CM C07

Salivary Gland Cancer

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM C07 • 8 Linked .gov / PubMed Citations • Governance: Dr. Devon Caldwell, DO, MPH (NPI #1568063758)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Salivary Gland Cancer Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

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What Is Salivary Gland Cancer?

Your salivary glands make saliva - sometimes called spit - and empty it into your mouth through openings called ducts. Saliva makes your food moist, which helps you chew and swallow. It helps you digest your food. It also cleans your mouth and contains antibodies that can kill germs. Salivary gland cancer is a type of head and neck cancer . It is rare. It may not cause any symptoms, or you could notice: A lump in your ear, cheek, jaw, lip, or inside the mouth Fluid draining from your ear Trouble swallowing or opening the mouth widely Numbness, weakness, or pain in your face Doctors diagnose salivary gland cancer using a physical exam, imaging tests, and a biopsy.

Pathophysiology, Underlying Causes & Clinical Presentation

Underlying Salivary Gland Cancer (code C07) is immune-checkpoint evasion [Salivary Gland Cancer C07], Cross-referenced with NIH MeSH (Salivary Gland Neoplasms), which Cancer, Oncology & Supportive Care clinicians address while surveilling Comprehensive Metabolic & in Salivary Gland Cancer (C07: Organ Function Panel) (Preserved renal/hepatic clearance (C07)).

Common Symptoms & Clinical Signs

  • • A lump in your ear, cheek, jaw, lip, or inside the mouth
  • • Fluid draining from your ear
  • • Presentation of Salivary Gland Cancer (C07): unintended weight loss [Salivary Gland Cancer C07]
  • • Secondary Salivary Gland Cancer clinical sign: unexplained bleeding, chronic in Salivary Gland Cancer (C07: hoarseness/cough, or progressive)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Salivary Gland Cancer Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code C07 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Cancer, Oncology & Supportive Care NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Comprehensive Metabolic & in Salivary Gland Cancer (C07: Organ Function Panel) Preserved renal/hepatic clearance (C07) Clinical Reference Target Range
Diagnostic / Lab Marker: Pathology / Molecular in Salivary Gland Cancer (C07: Genomic Staging) Guideline-concordant surveillance (C07) Clinical Reference Target Range
Diagnostic / Lab Marker: Complete Blood Count in Salivary Gland Cancer (C07: (ANC, Hemoglobin, Platelets)) Safe hematologic reserve (C07) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Salivary Gland Cancer

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Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Glycopyrrolate Cuvposa, Glyrx-Pf • RxCUI 238212 Anticholinergic 85% $1.2855 $ 6.98 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Salivary Gland Cancer)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Veliparib with carboplatin and paclitaxel in BRCA-mutated advanced breast cancer: What a 509-Participant Study Found

Final OS data indicate that the PFS improvement shown in the primary analysis did not translate into an OS benefit.

European journal of cancer (Oxford, England : 1990) • 2024-03-15 • Phase III Randomized Trial
N = 509 93/100 PMID 38309017 ↗
New Insights on Identifying optimal clinical trial candidates for locoregionally advanced: What a 9,468-Participant Study Found

N2-3 or T4 NPC patients were ideal candidates for multicenter clinical trials in locoregionally advanced NPC.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology • 2022-02-15 • Phase III Randomized Trial
N = 9,468 90/100 PMID 34971660 ↗
New Insights on Does three-dimensional surgery affect recurrence patterns in patients with: What a 419-Participant Study Found

3D-LG for GC did not differ significantly from 2D-LG in the effects on 3-year recurrence patterns, RFS and OS, which provides more tumor-related evidence for 3D technology.

Surgical endoscopy • 2021-01-15 • Phase III Randomized Trial
N = 419 87/100 PMID 31953725 ↗
What the Latest Evidence Really Says About Associations Between Morning Salivary and Blood Cortisol Concentrations in

Cortisol concentrations did not differ between adults with OSAS and healthy controls.

Frontiers in endocrinology • 2020-01-15 • Meta-Analysis
Multi-cohort 86/100 PMID 33542703 ↗
Can This Approach Help? Inside the Latest Research on Neoadjuvant chemoradiation with or without PD-1 blockade in locally advanced

Our results show that adding PD-1 blockade after neoadjuvant chemoradiation increases the pCR rate for patients with LARC and raises no substantial safety concerns.

Nature medicine • 2025-02-15 • Phase III Randomized Trial
Multi-cohort 82/100 PMID 39762418 ↗
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Salivary Gland Cancer Patient Community & “People Like Me” Threads

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