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Cancer, Oncology & Supportive Care • ICD-10-CM C62.90

Testicular Cancer

Also known as: Testis, Testes, Testicular, Testicle

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM C62.90 • 8 Linked .gov / PubMed Citations • Governance: Dr. Devon Caldwell, DO, MPH (NPI #1568063758)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Testicular Cancer Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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3 of 3 Free Questions Remaining

What Is Testicular Cancer?

What is testicular cancer? Testicular cancer is a cancer that develops in the tissues of one or both testicles. The testicles, or testes, are part of the male reproductive system. They make male hormones and sperm. They are two egg-shaped glands inside the scrotum, a sac of loose skin that lies below the penis. You can get cancer in one or both testicles. Who is most likely to develop testicular cancer? Testicular cancer is very rare. You can get it at any age, but it is most common in men between the ages of 20 and 39.

Pathophysiology, Underlying Causes & Clinical Presentation

Biological expression of Testicular Cancer (C62.90, Cancer & Oncology) reflects tumor-suppressor loss enabling in Testicular Cancer (C62.90: clonal proliferation). Cross-referenced with NIH MeSH (Testicular Neoplasms), longitudinal control is benchmarked via Complete Blood Count in Testicular Cancer (C62.90: (ANC, Hemoglobin, Platelets)).

Common Symptoms & Clinical Signs

  • • Have had abnormal testicle development
  • • Have had an undescended testicle, a condition in which one or both testicles fail to move into the scrotum before birth
  • • Presentation of Testicular Cancer (C62.90): unintended weight loss [Testicular Cancer C62.90]
  • • Secondary Testicular Cancer clinical sign: unexplained bleeding, chronic in Testicular Cancer (C62.90: hoarseness/cough, or progressive)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Testicular Cancer Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code C62.90 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Cancer, Oncology & Supportive Care NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Complete Blood Count in Testicular Cancer (C62.90: (ANC, Hemoglobin, Platelets)) Safe hematologic reserve (C62.90) Clinical Reference Target Range
Diagnostic / Lab Marker: Comprehensive Metabolic & in Testicular Cancer (C62.90: Organ Function Panel) Preserved renal/hepatic clearance (C62.90) Clinical Reference Target Range
Diagnostic / Lab Marker: Pathology / Molecular in Testicular Cancer (C62.90: Genomic Staging) Guideline-concordant surveillance (C62.90) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Testicular Cancer

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Treatment selection for Testicular Cancer depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Testicular Cancer)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Glucagon-like peptide 1 receptor agonists on testicular: What a 680-Participant Study Found

Our systematic review and meta-analysis suggest a possible role for GLP-1RAs in the therapy of functional hypogonadism related to overweight and obesity, while also promoting weight loss.

Andrology • 2025-11-15 • Meta-Analysis
N = 680 91/100 PMID 40105090 ↗
New Insights on Transcriptomic profiling of adjuvant colorectal cancer identifies three key: What a 1,062-Participant Study Found

This work furthers our understanding of the underlying biology that propagates stage II/III CRC disease progression and provides scientific rationale for future high-risk stratification and targeted treatment evaluation in...

PloS one • 2021-01-15 • Phase III Randomized Trial
N = 1,062 90/100 PMID 34972191 ↗
Can This Approach Help? Inside the Latest Research on Effects of short-term oral phytoestrogen supplementation on the

Phytoestrogen treatment interferes with HPT axis in CaP patients by inducing testicular resistance to LH and compensated hypogonadism.

The Prostate • 2006-07-01 • Randomized Controlled Trial
N = 40 88/100 PMID 16637075 ↗
New Insights on Induction TPF versus adjuvant PF after CCRT in locally advanced nasopharyngeal: What a 266-Participant Study Found

In this randomized clinical trial, IC did not improve 3-year PFS for LA-NPC patients and increased hematological toxicity.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology • 2026-10-15 • Phase III Randomized Trial
N = 266 87/100 PMID 42604670 ↗
What the Latest Evidence Really Says About Testosterone deficiency in testicular cancer survivors - a systematic review and

Strong evidence exists that standard CT, non-conventional therapy and infradiaphragmatic RT are associated with an increased risk of TD in TGCC-patients when compared with orchiectomy alone.

Andrology • 2016-05-15 • Meta-Analysis
Multi-cohort 86/100 PMID 27009402 ↗
Zero-PHI Patient Support & Cohort Discussions

Testicular Cancer Patient Community & “People Like Me” Threads

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