dotMD.com
Cancer, Oncology & Supportive Care • ICD-10-CM D49.89

Thymus Cancer

Also known as: Thymoma

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM D49.89 • 8 Linked .gov / PubMed Citations • Governance: Dr. Devon Caldwell, DO, MPH (NPI #1568063758)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Thymus Cancer Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

Ask our AI Specialists anything about Thymus Cancer

3 of 3 Free Questions Remaining

What Is Thymus Cancer?

The thymus is a small organ in your upper chest, under your breastbone. Before birth and during childhood, the thymus helps the body make a type of white blood cell. These cells help protect you from infections. Cancer of the thymus is rare. You are more likely to get it if you have other diseases such as myasthenia gravis, lupus or rheumatoid arthritis. Sometimes there are no symptoms. Other times, thymus cancer can cause: A cough that doesn't go away Chest pain Trouble breathing Doctors use a physical exam, imaging tests, and a biopsy to diagnose thymus cancer. The most common treatment is surgery to remove the tumor.

Pathophysiology, Underlying Causes & Clinical Presentation

At the cellular and tissue level in cancer & oncology, Thymus Cancer (D49.89) involves local tissue remodeling [Thymus Cancer D49.89]. Cross-referenced with NIH MeSH (Thymus Neoplasms), progression correlates with shifts in Complete Blood Count in Thymus Cancer (D49.89: (ANC, Hemoglobin, Platelets)) (Safe hematologic reserve (D49.89)).

Common Symptoms & Clinical Signs

  • • A cough that doesn't go away
  • • Presentation of Thymus Cancer (D49.89): unexplained bleeding, chronic in Thymus Cancer (D49.89: hoarseness/cough, or progressive)
  • • Secondary Thymus Cancer clinical sign: abnormality detected early in Thymus Cancer (D49.89: on age-appropriate screening)
  • • Symptom flares in Thymus Cancer correlating with Complete Blood Count in Thymus Cancer (D49.89: (ANC, Hemoglobin, Platelets)) deviation outside Safe hematologic reserve (D49.89)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Thymus Cancer Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code D49.89 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Cancer, Oncology & Supportive Care NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Complete Blood Count in Thymus Cancer (D49.89: (ANC, Hemoglobin, Platelets)) Safe hematologic reserve (D49.89) Clinical Reference Target Range
Diagnostic / Lab Marker: Comprehensive Metabolic & in Thymus Cancer (D49.89: Organ Function Panel) Preserved renal/hepatic clearance (D49.89) Clinical Reference Target Range
Diagnostic / Lab Marker: Pathology / Molecular in Thymus Cancer (D49.89: Genomic Staging) Guideline-concordant surveillance (D49.89) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Thymus Cancer

Check Drug Interactions →
Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Rethymic (Allogenic Thymocyte-Depleted Thymus Tissue-Agdc) Rethymic • RxCUI RXN-B72359001 FDA Prescription Therapeutic Agent 94% $2.9100 $ 218.02 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Thymus Cancer)

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Gold-standard blind clinical trial comparing safety and real-world benefits of: What a 357-Participant Study Found

The results of this study demonstrated therapeutic equivalence of bevacizumab biosimilar BCD-021 and referent bevacizumab drug.

BMC cancer • 2022-02-01 • Phase III Randomized Trial
N = 357 93/100 PMID 35105329 ↗
New Insights on Phase III Randomized Trial of Maintenance Taxanes Versus Surveillance in Women: What a 1,157-Participant Study Found

Maintenance therapy with P and PP did not improve OS among patients with newly diagnosed O/tubal/peritoneal cancer, but may modestly increase PFS.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2022-12-10 • Phase III Randomized Trial
N = 1,157 90/100 PMID 35759733 ↗
Can This Approach Help? Inside the Latest Research on Treatment-Related Changes in Cerebrospinal Fluid Markers of Oxidative Stress and

Analysis of CSF collected prospectively in a large cohort of children treated for ALL demonstrated significant changes in markers of oxidative stress and neurodegeneration within three.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology • 2025-11-03 • Phase III Randomized Trial
Multi-cohort 82/100 PMID 40905823 ↗
Can This Approach Help? Inside the Latest Research on Safety and real-world benefits of total mesorectal excision (TME) surgery

Dose escalation can facilitate nonsurgical treatment for cT2-3 rectal cancer patients who are fit but wish to avoid TME surgery and stoma.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland • 2023-11-15 • Phase III Randomized Trial
N = 148 82/100 PMID 37837240 ↗
Can This Approach Help? Inside the Latest Research on Randomized, controlled clinical trial of adjuvant sintilimab for esophageal

The results of this randomized controlled trial addressed controversy regarding the survival benefits of adjuvant sintilimab treatment for patients with resected locally advanced ESCC.

Future oncology (London, England) • 2023-08-15 • Phase III Randomized Trial
Multi-cohort 82/100 PMID 37737025 ↗
Zero-PHI Patient Support & Cohort Discussions

Thymus Cancer Patient Community & “People Like Me” Threads

“People Like Me” Cohort Filter (Zero-PHI)

Filter Thymus Cancer community threads and patient logs by age, biological sex, dosage, and treatment duration.

No threads match this cohort filter yet. Click + Start Anonymous Discussion to ask the community about Thymus Cancer.

Related Conditions in Cancer, Oncology & Supportive Care