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Cancer, Oncology & Supportive Care • ICD-10-CM C55

Uterine Cancer

Also known as: Endometrial cancer, Uterus, Womb, Myometrium, Uterine

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM C55 • 8 Linked .gov / PubMed Citations • Governance: Dr. Devon Caldwell, DO, MPH (NPI #1568063758)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Uterine Cancer Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Uterine Cancer?

What is uterine cancer? Uterine cancer is a cancer that forms in tissues of the uterus , which is sometimes called the womb. The uterus is the place where a fetus grows during pregnancy. There are two types of uterine cancer: Endometrial cancer is the most common type. This type of cancer begins in the cells lining the uterus, known as the endometrium. Uterine sarcoma is a rare, more aggressive cancer that is harder to treat. This type of cancer begins in muscle or other tissues in the uterus. Who is more likely to develop uterine cancer? Uterine cancer usually happens after menopause. The cause is unknown.

Pathophysiology, Underlying Causes & Clinical Presentation

Uterine Cancer (C55) alters cancer & oncology homeostasis through local tissue remodeling [Uterine Cancer C55]; Cross-referenced with NIH MeSH (Uterine Neoplasms), clinical remission targets Comprehensive Metabolic & in Uterine Cancer (C55: Organ Function Panel) within Preserved renal/hepatic clearance (C55).

Common Symptoms & Clinical Signs

  • • Endometrial cancer is the most common type. This type of cancer begins in the cells lining the uterus, known as the endometrium
  • • Uterine sarcoma is a rare, more aggressive cancer that is harder to treat. This type of cancer begins in muscle or other tissues in the uterus
  • • Presentation of Uterine Cancer (C55): unexplained bleeding, chronic in Uterine Cancer (C55: hoarseness/cough, or progressive)
  • • Secondary Uterine Cancer clinical sign: abnormality detected early in Uterine Cancer (C55: on age-appropriate screening)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Uterine Cancer Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code C55 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Cancer, Oncology & Supportive Care NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Complete Blood Count in Uterine Cancer (C55: (ANC, Hemoglobin, Platelets)) Safe hematologic reserve (C55) Clinical Reference Target Range
Diagnostic / Lab Marker: Comprehensive Metabolic & in Uterine Cancer (C55: Organ Function Panel) Preserved renal/hepatic clearance (C55) Clinical Reference Target Range
Diagnostic / Lab Marker: Pathology / Molecular in Uterine Cancer (C55: Genomic Staging) Guideline-concordant surveillance (C55) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Uterine Cancer

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Treatment selection for Uterine Cancer depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Uterine Cancer)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Pain Reduction in Linzagolix-Treated Patients With Uterine Fibroids: A Secondary: What a 1,012-Participant Study Found

This analysis showed that reductions in pain were significantly mediated by reductions in HMB (all doses) and FV (200 mg alone) in linzagolix-treated women with UFs.

BJOG : an international journal of obstetrics and gynaecology • 2025-08-15 • Phase III Randomized Trial
N = 1,012 96/100 PMID 40326221 ↗
New Insights on Relugolix combination therapy in European women with symptomatic uterine: What a 388-Participant Study Found

In European women with UF and HMB, once-daily relugolix-CT vs.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology • 2023-08-17 • Phase III Randomized Trial
N = 388 93/100 PMID 37634528 ↗
New Insights on Implementation of the Study Participant Feedback Questionnaire to understand: What a 371-Participant Study Found

Participants reported positive experiences in the INTERLINK-1 study as evaluated by the SPFQ.

BMJ open • 2025-10-28 • Phase III Randomized Trial
N = 371 93/100 PMID 41151963 ↗
What the Latest Evidence Really Says About Effects of sildenafil citrate on intrauterine growth

Sildenafil citrate increases birth weight and prolonged pregnancies but did not affect stillbirth rate, neonatal death, and NICU admission.

BMC pregnancy and childbirth • 2023-06-02 • Meta-Analysis
Multi-cohort 92/100 PMID 37268873 ↗
Can This Approach Help? Inside the Latest Research on QuANTUM-First: Clinical Validation of the LeukoStrat Companion Diagnostic for the

The OS benefit provided by quizartinib in.

Archives of pathology & laboratory medicine • 2025-09-02 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 40892059 ↗
Zero-PHI Patient Support & Cohort Discussions

Uterine Cancer Patient Community & “People Like Me” Threads

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