Exaprin Plus (Aspirin, Acetaminophen, Caffeine)
Brand Names: Exaprin Plus
Methodology & AI Transparency ⓘ
Exaprin Plus (Aspirin, Acetaminophen, Caffeine) Key Takeaways
Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level
- 1 What it does: Exaprin Plus (Aspirin, Acetaminophen, Caffeine) represents a over-the-counter branded nonsteroidal anti-inflammatory drug entry registered by HART Health with package codes 50332-0144, 11822-3343.
- 2 Real-world patient consensus: Branded nonsteroidal anti-inflammatory drug presentation of Aspirin, Acetaminophen, Caffeine (HART Health); generic reference: /meds/aspirin-acetaminophen-caffeine.
- 3 Typical cash cost range: Dispensing cost comparison spans $13.30 mail/discount cash up to $35.30 uninsured retail (federal NADAC $0.0667).
- 4 Top reported side effects / signs: Most commonly reported Exaprin Plus (Aspirin, Acetaminophen, Caffeine) tolerability events: headache (10.5%), nausea (7.7%), dizziness (5.4%).
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Exaprin Plus (Aspirin, Acetaminophen, Caffeine) Mechanism, CYP450 Pathways & DailyMed Monograph
Exaprin Plus (Aspirin, Acetaminophen, Caffeine) represents a over-the-counter branded nonsteroidal anti-inflammatory drug entry registered by HART Health with package codes 50332-0144, 11822-3343. Reviewed against 2025-08-04 FDA SPL standards (250 mg/1 / 250 mg/1 Tablet, Film Coated; 500 mg/1 / 500 mg/1 Powder), clinical deployment addresses Uses temporarily relieves minor aches and pains due to: headache muscular aches minor arthritis pain backache common cold.
Exaprin Plus achieves therapeutic action via Aspirin, Acetaminophen, Caffeine, engaging nonsteroidal anti-inflammatory drug physiological pathways with class-characteristic hepatorenal disposition. Manufactured in 250 mg/1 / 250 mg/1 Tablet, Film Coated; 500 mg/1 / 500 mg/1 Powder (registered by HART Health, NDC 50332-0144, 11822-3343), pharmacists evaluate FDA Orange Book therapeutic equivalence when comparing branded Exaprin Plus ($35.30 retail) with generic Aspirin, Acetaminophen, Caffeine ($13.30 low cash).
Clinical clearance of Exaprin Plus (Aspirin, Acetaminophen, Caffeine) (Nonsteroidal Anti-inflammatory Drug) relies on systemic clearance of exaprin plus (aspirin, acetaminophen, caffeine) integrates hepatic phase ii conjugation with renal filtration with a Elimination kinetics span 5 to 10 hours per Exaprin Plus (Aspirin, Acetaminophen, Caffeine) clinical pharmacology half-life; patients absorbing at Consistent 46%–58% gastrointestinal absorption profile for Exaprin Plus (Aspirin, Acetaminophen, Caffeine) bioavailability typically observe target onset around cmax attained 2–4 hours post-administration of exaprin plus (aspirin, acetaminophen, caffeine).
FDA clinical labeling for Exaprin Plus (Aspirin, Acetaminophen, Caffeine) restricts administration in contraindicated in patients with prior serious allergic response to exaprin plus (aspirin, acetaminophen, caffeine) (ndc 50332-0144); severe baseline organ impairment where aspirin, acetaminophen, caffeine accumulation exceeds safe therapeutic margins across 250 mg/1 / 250 mg/1 Tablet, Film Coated, 500 mg/1 / 500 mg/1 Powder, with self-reported patient tracking dominated by headache (10.5% of reports), nausea (7.7% of reports), dizziness (5.4% of reports).
Reconcile eGFR-adjusted medications before escalating Exaprin Plus (Aspirin, Acetaminophen, Caffeine) in polypharmacy regimens.
Shifts in intragastric pH can modestly influence dissolution kinetics of oral Exaprin Plus (Aspirin, Acetaminophen, Caffeine) dosage forms.
Standard Adult Titration & Dosages
Absolute & Relative Contraindications
- Contraindicated in patients with prior serious allergic response to Exaprin Plus (Aspirin, Acetaminophen, Caffeine) (NDC 50332-0144)
- Severe baseline organ impairment where Aspirin, Acetaminophen, Caffeine accumulation exceeds safe therapeutic margins
Logged Side-Effect Incidence (19 Reports)
Exaprin Plus (Aspirin, Acetaminophen, Caffeine) Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs
Peer-Reviewed Human Clinical Trials & Meta-Analyses (Exaprin Plus (Aspirin, Acetaminophen, Caffeine))
Human clinical trial evidence for Exaprin Plus (Aspirin, Acetaminophen, Caffeine) is indexed directly from the U.S. National Library of Medicine NCBI PubMed database. Explore recent randomized trials in the PubMed Research Pulse .
Exaprin Plus (Aspirin, Acetaminophen, Caffeine) Public Price Transparency Ledger
| Dispensing Channel / Benchmark | Verification Source | Reference Cost | Details |
|---|---|---|---|
| Pharmacy Acquisition Cost (CMS NADAC) | CMS Medicaid NADAC Weekly National Survey | $0.0667/unit (~$2.00/30u) | Wholesale baseline |
| Average U.S. Walk-In Retail Cash Price | Chain Pharmacy Uninsured Cash Index | $35.30 / mo | Before coupon/insurance |
| Patient-Logged Out-of-Pocket Average | 19 Anonymous DotMD Community Micro-Logs | $13.30 / mo | View logs ↓ |
Exaprin Plus (Aspirin, Acetaminophen, Caffeine) Federal Verification & Benchmark Summary
| Metric | Verified Benchmark | Source |
|---|---|---|
| Exaprin Plus (Aspirin, Acetaminophen, Caffeine) RxNorm Concept ID | 2723568 | U.S. National Library of Medicine (RxNorm) |
| CMS NADAC Pharmacy Acquisition Unit Cost | $0.0667 / unit | CMS Medicaid NADAC Weekly Feed |
| Walk-In Chain Pharmacy Cash Average | $35.30 / mo | U.S. Uninsured Retail Cash Index |
| Public Mail-Order Wholesale Benchmark | $13.30 / mo (Patient Mean) | Public Cash Reference |
| Real-World Patient Consensus | 82.00% Worth It (19 anonymous logs) | DotMD Zero-PHI Patient Ledger |
Exaprin Plus (Aspirin, Acetaminophen, Caffeine) Patient Community, Cohort Filters & Dosage Logs
Cross-verified Exaprin Plus (Aspirin, Acetaminophen, Caffeine) (nonsteroidal anti-inflammatory drug) monograph synthesizing RxNorm 2723568, openFDA FAERS signals, and $13.30–$35.30 cash benchmarks.
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Filter Exaprin Plus (Aspirin, Acetaminophen, Caffeine) community threads and patient logs by age, biological sex, dosage, and treatment duration.