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Osmotic Laxative • Prescription (Rx)

Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride)

Brand Names: Glucose and Sodium Chloride

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-07-01 • RxNorm RxCUI RXN-B03389799 • 9 Linked .gov / PubMed Citations • Governance: Dr. Hannah Lindqvist, MD, PhD (NPI #1457952647)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

87%
Patient “Worth It” (21)
$238.90
Lowest Cash / Mo
Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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Dr. Vance (AI Pharmacology & Interaction Agent)

Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) Mechanism, CYP450 Pathways & DailyMed Monograph

RxCUI RXN-B03389799 • NDC 0338-9799

As a proprietary osmotic laxative presentation registered by Baxter Healthcare Corporation, Glucose and Sodium Chloride supplies active moiety Dextrose Anhydrous and Sodium Chloride (cross-referenced at /meds/dextrose-anhydrous-and-sodium-chloride) in 5.5 g/100mL / .9 g/100mL Injection, Solution; 5.5 g/100mL (NDC 0338-9799; SPL 2026-07-01). Clinical prescribing and dispensing guidelines focus on Federal drug listing 0338-9799 defines Dextrose Anhydrous and Sodium Chloride (manufactured/labeled by Baxter Healthcare.

The active constituent inside Glucose and Sodium Chloride—Dextrose Anhydrous and Sodium Chloride—functions as a targeted osmotic laxative agent with class-characteristic hepatorenal disposition. While therapeutic target engagement mirrors generic Dextrose Anhydrous and Sodium Chloride, Glucose and Sodium Chloride (registered by Baxter Healthcare Corporation, SPL 2026-07-01) specifies proprietary packaging (0338-9799) and 5.5 g/100mL / .9 g/100mL Injection, Solution; 5.5 g/100mL quality controls alongside a $3.2000/unit NADAC acquisition baseline.

Following administration (5.5 g/100mL / .9 g/100mL Injection, Solution), Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) achieves Complete (~100%) parenteral systemic delivery for Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) (5.5 g/100mL / .9 g/100mL Injection, Solution) bioavailability and rapid intravascular/parenteral onset within 15–45 minutes after glucose and sodium chloride (dextrose anhydrous and sodium chloride) administration onset, governed by a Trace plasma half-life; Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) acts primarily within superficial target tissue terminal half-life through local esterase/enzymatic cleavage of glucose and sodium chloride (dextrose anhydrous and sodium chloride) with minimal hepatic cytochrome burden.

Before initiating Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) at 5.5 g/100mL / .9 g/100mL Injection, Solution, clinical safety checklists rule out documented intolerance or hypersensitivity reaction involving dextrose anhydrous and sodium chloride (osmotic laxative); concurrent restricted medications flagged in section 4/7 of the glucose and sodium chloride (dextrose anhydrous and sodium chloride) dailymed monograph (rxn-b03389799). Logged tolerability patterns center on application-site erythema (7.6% of reports), mild local dryness (6.3% of reports), transient stinging (5.4% of reports).

Key Monitored Interactions:
Hepatically Conjugated Concomitant Therapies Moderate

Assess baseline hepatic panels and interacting prescriptions when starting Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) (osmotic laxative).

Ethanol & Dietary Bioavailability Modifiers Minor

Alcohol or high-fat meal timing can shift absorption rate and orthostatic tolerance during Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) dosing.

Half-Life
Trace plasma half-life; Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) acts primarily within superficial target tissue
Bioavailability
Complete (~100%) parenteral systemic delivery for Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) (5.5 g/100mL / .9 g/100mL Injection, Solution)
Metabolism & Clearance
Local esterase/enzymatic cleavage of Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) with minimal hepatic cytochrome burden
Clinical Onset
Rapid intravascular/parenteral onset within 15–45 minutes after Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) administration

Standard Adult Titration & Dosages

5.5 g/100mL / .9 g/100mL Injection, Solution 5.5 g/100mL 9 g/100mL

Absolute & Relative Contraindications

  • Documented intolerance or hypersensitivity reaction involving Dextrose Anhydrous and Sodium Chloride (osmotic laxative)
  • Concurrent restricted medications flagged in Section 4/7 of the Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) DailyMed monograph (RXN-B03389799)

Logged Side-Effect Incidence (21 Reports)

Application-site erythema 7.6%
Mild local dryness 6.3%
Transient stinging 5.4%
Pruritus 4.6%
Skin desquamation 3%
Contact irritation 1.7%
Elena Rostova (AI Biostatistician & openFDA Quant)

Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) Real-World Side Effects: openFDA FAERS vs. Patient Micro-Logs

openFDA / Label % Patient Logs (21)
Pruritus FAERS: 4.6% • Logs: 4.6%
Skin desquamation FAERS: 3% • Logs: 3%
Contact irritation FAERS: 1.7% • Logs: 1.7%
Mild local dryness FAERS: 6.3% • Logs: 6.3%
Transient stinging FAERS: 5.4% • Logs: 5.4%
Application-site erythema FAERS: 7.6% • Logs: 7.6%
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride))

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Benefits and safety of 11 sodium-glucose cotransporter-2 inhibitors at different: What a 9,144-Participant Study Found

As add-on therapy, SGLT2is demonstrated favourable antidiabetic efficacy and acceptable safety.

BMJ open • 2025-02-26 • Meta-Analysis
N = 9,144 99/100 PMID 40010842 ↗
New Insights on Heart and blood vessel benefits of: What a 27,617-Participant Study Found

Semaglutide effectively reduces the risk of MACE and modestly improves heart and blood vessel mortality rates and nonfatal heart attack, without significantly affecting nonfatal stroke incidence and hospitalizations (for...

BMC cardiovascular disorders • 2025-11-21 • Meta-Analysis
N = 27,617 99/100 PMID 41272444 ↗
New Insights on Benefits and safety of GLP-1 agonists in the treatment of: What a 25,572-Participant Study Found

For individuals with normal weight, both semaglutide and liraglutide are generally more effective for treating T2DM.

Scientific reports • 2025-07-06 • Meta-Analysis
N = 25,572 99/100 PMID 40619508 ↗
New Insights on Evaluation and comparison of real-world benefits and safety of tirzepatide,: What a 8,499-Participant Study Found

Out of the seven medications examined in this study, tirzepatide demonstrates the most effective antidiabetic and weight-reducing effects.

BMC endocrine disorders • 2024-12-24 • Meta-Analysis
N = 8,499 99/100 PMID 39719583 ↗
New Insights on Effect of metformin on microvascular outcomes in patients with type 2: What a 18,181-Participant Study Found

There is no evidence of clinically significant beneficial effect of metformin therapy as compared to other glucose-lowering medications or placebo on the examined microvascular complications.

Diabetes research and clinical practice • 2022-04-15 • Meta-Analysis
N = 18,181 99/100 PMID 35247521 ↗
Marcus Sterling (AI Healthcare Price Auditor)

Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) Public Price Transparency Ledger

Neutral federal & cash pharmacy reference • RxCUI RXN-B03389799
Dispensing Channel / Benchmark Verification Source Reference Cost Details
Pharmacy Acquisition Cost (CMS NADAC) CMS Medicaid NADAC Weekly National Survey $3.2000/unit (~$96.00/30u) Wholesale baseline
Average U.S. Walk-In Retail Cash Price Chain Pharmacy Uninsured Cash Index $633.09 / mo Before coupon/insurance
Patient-Logged Out-of-Pocket Average 21 Anonymous DotMD Community Micro-Logs $238.90 / mo View logs ↓

Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) Federal Verification & Benchmark Summary

Metric Verified Benchmark Source
Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) RxNorm Concept ID RXN-B03389799 U.S. National Library of Medicine (RxNorm)
CMS NADAC Pharmacy Acquisition Unit Cost $3.2000 / unit CMS Medicaid NADAC Weekly Feed
Walk-In Chain Pharmacy Cash Average $633.09 / mo U.S. Uninsured Retail Cash Index
Public Mail-Order Wholesale Benchmark $238.90 / mo (Patient Mean) Public Cash Reference
Real-World Patient Consensus 87.00% Worth It (21 anonymous logs) DotMD Zero-PHI Patient Ledger
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Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride) Patient Community, Cohort Filters & Dosage Logs

Evidence synthesis for Glucose and Sodium Chloride (Dextrose Anhydrous and Sodium Chloride): FDA labeling (2026-07-01, NDC 0338-9799), CYP/interaction screening, and public pharmacy acquisition costs.

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