✓ Translated by DotMD AI Clinical Council Source: Nutrients • Randomized Controlled Trial
Verify Primary Source: NIH PubMed PMID #37571251 ↗

Randomized Controlled Trial: Effects of Unripe Black Raspberry Extract Supplementation on Male Climacteric Syndrome and Voiding Dysfunction: A Pilot, Randomized, Double-Blind, Placebo-Controlled Trial (N = 30)

Original Paper Title: “Effects of Unripe Black Raspberry Extract Supplementation on Male Climacteric Syndrome and Voiding Dysfunction: A Pilot, Randomized, Double-Blind, Placebo-Controlled Trial”

Elena Rostova (AI Quant) Rigor Score
88 / 100
Sample Size (Participants)
N = 30
Evidence Classification
Randomized Controlled Trial
Sarah Jenkins, RN (AI Plain-English Editor) • Key Takeaways
  • In the BRE group, the total IPSS and IPSS-QoL scores decreased significantly after 12 weeks compared to baseline ( p p < 0.05).
  • Study Design & Sample: Randomized Controlled Trial published in Nutrients (N = 30 human participants).
  • Biostatistical Rigor Score: 88/100 audited by Elena Rostova (AI Biostatistician & openFDA Quant).

What the Study Found (In Plain English)

Published in Nutrients (2023), this randomized controlled trial evaluating 30 human participants investigated: Male climacteric syndrome (MCS) is a medical condition that can affect middle-aged men whose testosterone levels begin to decline considerably. Key clinical takeaway: In the BRE group, the total IPSS and IPSS-QoL scores decreased significantly after 12 weeks compared to baseline ( p p < 0.05).

Dr. Lin (AI Evidence Lead): Statistical Endpoints & Numbers

Primary Endpoint & Quantitative Summary (Nutrients, 2023-07-26; N = 30; Rigor 88/100): In the BRE group, the total IPSS and IPSS-QoL scores decreased significantly after 12 weeks compared to baseline ( p p < 0.05).

Study Limitations & Caveats Before You Act

Clinical trials evaluate specific inclusion/exclusion cohorts under protocol-controlled conditions (Randomized Controlled Trial). Individual response, hepatic/renal clearance, CYP450 drug interactions, and baseline comorbidities vary; verify applicability with a board-certified physician before modifying any prescription or supplement regimen.

Related DotMD Clinical Hubs & Price Ledgers

Rx: quality-choice-effervescent-cold-relief-plus-aspirin-chlorpheniramine → Rx: quality-choice-pain-relief-powder-aspirin-and-caffeine → Rx: testosterone-cypionate → Rx: testosterone → Condition: erectile-dysfunction-bph → Condition: erectile-dysfunction →
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