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NIH Office of Dietary Supplements (DSLD v9) • Drug-Supplement Interactions

Dietary Supplements, Vitamins & Peptides (585)

Evidence-based guides to active ingredients, clinical trial dosages, prescription drug interactions (CYP450, bleeding, and absorption pathways), and anonymous patient micro-logs.

All Categories Neurotrophic B-Vitamins & Methylation (20) Essential Minerals & Electrolytes (17) Fat-Soluble Vitamins & Bone Health (17) Joint Cartilage & Mobility (16) Seasonal Immune Botanicals (16) Joint & Systemic Inflammation (10) Neuropathy & Glycemic Antioxidants (10) Cognitive Focus & Calm (10) Adaptogens & Stress Resilience (10) Mast-Cell, Allergy & Senolytic Flavonoids (10) Hepatoprotective Botanicals (9) NIH DSLD Cordyceps Formulations (9) NIH DSLD Manganese Formulations (9) Neuronal Membrane Phospholipids (9) NIH DSLD Copper Formulations (9) Mitochondrial & Cardiovascular (9) Sleep & Circadian Chronobiotics (9) NIH DSLD Boron Formulations (9) Stress & Autonomic Relaxation (9) Muscle, Longevity & Neuroenergetics (9) Cardiometabolic Lipids (9) Essential Minerals & Immune Defense (9) Microbiome & Gut Barrier (9) Polyphenols & Vascular Longevity (9) Thyroid & Prenatal Trace Minerals (9) Sleep Thermoregulation & Collagen Synthesis (8) NIH DSLD Molybdenum Formulations (8) NIH DSLD Betaine HCl Formulations (8) Serotonergic Precursors (Interaction Alert) (8) Joint & Mucosal 5-LOX Botanicals (8) Hematology & Oxygen Transport (8) Vascular Endothelial Amino Acids (8) Botanical Sleep Support (8) Urology & Prostate Health (8) PCOS, Fertility & Insulin Signaling (8) Cellular NAD+ & Mitochondrial Longevity (8) Cardiometabolic & Osmolyte Amino Acids (8) Cellular Detox & Redox (8) Dermatology, Tendon & Joint Matrix (8) Metabolic & Glycemic Botanicals (8) NIH DSLD Garlic Formulations (8) Ophthalmology & Macular Pigment (8) Thyroid & Redox Trace Minerals (8) Adaptogens & Mental Stamina (8) Collagen, Iron Uptake & Antioxidant (8) NIH DSLD Niacinamide Formulations (7) Vascular Endothelial & Exercise Performance (7) NIH DSLD Electrolytes Formulations (7) NIH DSLD Pantothenic Acid Formulations (7) NIH DSLD Beet Root Formulations (7) NIH DSLD Biotin Formulations (7) Cerebral Microcirculation & Tinnitus (7) Metabolic Trace Minerals (7) Vascular Calcification & Bone Matrix (7) NIH DSLD Vitamin A Formulations (7) Mitochondrial Fatty-Acid & Neuro-Support (7) Neurotrophic Medicinal Mushrooms (7) NIH DSLD Green Tea Extract Formulations (7) Mood Botanicals (High Interaction Alert) (6) NIH DSLD Cranberry Formulations (6) NIH DSLD Digestive Enzymes Formulations (6) Soluble Prebiotic Fiber & LDL Lowering (6) NIH DSLD Reishi Formulations (6) Antioxidants, Hepatic & Respiratory (6) NIH DSLD Hyaluronic Acid Formulations (5) NIH DSLD Vitamin B6 Formulations (5) NIH DSLD Vitamin E Formulations (5) Investigational Peptides & Tissue Repair (2) Endocrine & Visceral Adiposity Peptides (1) Bile Acids & Cholestatic Hepatoprotection (1) Sexual Health & Melanocortin Peptides (1) Dermal UV, Ocular & Lipid Carotenoids (1) TCA Cycle & Epigenetic Longevity (1) Mitochondrial Mitophagy & Longevity (1) Dermatology & Hair Peptides (1) Endocrine & Growth-Hormone Secretagogues (1) Nrf2 Cellular Detox & Antioxidant Defense (1) Autophagy & Cellular Longevity (1)
Hepatoprotective Botanicals DSLD #10941
Douglas Laboratories Milk Thistle

Formulated by Douglas Laboratories (NIH DSLD #10941), Douglas Laboratories Milk Thistle supplies Milk Thistle (Milk Thistle (Form: min. 80% Silymarin) PlantPart: fruit Note: dried extract) as an oral capsule. Utilized across liver & hepatology regimens, typical monthly outlay averages $22.04.

Typical: Manufacturer-listed Douglas Laboratories Milk Thistle capsule unit dose (#10941) ~$22/mo
Hepatoprotective Botanicals DSLD #242022
Fresh Nutrition Milk Thistle

Within Hepatoprotective Botanicals, Fresh Nutrition Milk Thistle (NIH DSLD Label #242022; Fresh Nutrition) furnishes Milk Thistle, Vitamin A Palmitate, Vitamin E (Milk Thistle (Form: 50% HPLC)) in softgel capsule form for structured daily supplementation.

Typical: Manufacturer-listed Fresh Nutrition Milk Thistle softgel capsule unit dose (#242022) ~$19/mo
Hepatoprotective Botanicals DSLD #224717
Higher Nature Milk Thistle

Higher Nature Milk Thistle is an NIH Office of Dietary Supplements DSLD-listed capsule product (Label #224717) delivering Milk Thistle fruits (Silybum marianum (L.) Gaetn.) standardised extract, Milk Thistle (Milk Thistle (Form: corresponding to Silymarin (Form: calculated as Silibinin) Note: 3.725g - 10.818g) PlantPart: fruits) within Hepatoprotective Botanicals. Clinical nutrition protocols deploy this Higher Nature formulation at ~$16.72/month for liver & hepatology support.

Typical: Standard Higher Nature Milk Thistle capsule serving per NIH DSLD #224717 ~$17/mo
Hepatoprotective Botanicals DSLD #34940
L.A. Naturals Milk Thistle

Within Hepatoprotective Botanicals, L.A. Naturals Milk Thistle (NIH DSLD Label #34940; L.A. Naturals) furnishes Milk Thistle, certified organic Milk Thistle (Milk Thistle (Form: 80% Silymarin) PlantPart: seed) in capsule form for structured daily supplementation.

Typical: Manufacturer-listed L.A. Naturals Milk Thistle capsule unit dose (#34940) ~$17/mo
Hepatoprotective Botanicals DSLD #46248
Milk Thistle Silymarin Phytosome (Silybum marianum)

Flavonolignan silybin complex supporting hepatocyte membrane stability, antioxidant glutathione preservation, and metabolic fatty-liver enzyme support.

Typical: 150 mg – 300 mg standardized 80% silymarin 2x daily ~$19/mo
Hepatoprotective Botanicals DSLD #251847
Nature's Way Milk Thistle

Cataloged in the federal NIH DSLD registry under ID #251847, Nature's Way Milk Thistle provides Milk Thistle seed extract, Blessed Thistle (Milk Thistle seed extract (Form: Standardized to 140 mg 80% Silymarin) PlantPart: seed) in a capsule matrix. Designed for hepatoprotective botanicals maintenance, it pairs label-verified composition with a 78% community rating.

Typical: Daily capsule intake of Nature's Way Milk Thistle with food (Label #251847) ~$16/mo
Hepatoprotective Botanicals DSLD #246621
Pure Synergy Superpure Milk Thistle

Pure Synergy Superpure Milk Thistle is an NIH Office of Dietary Supplements DSLD-listed capsule product (Label #246621) delivering Organic, SuperPure Milk Thistle (seed) extract, Organic, SuperPure Ethanol & H2O extract, Full Spectrum Flavonolignans Complex (Organic, SuperPure Milk Thistle (seed) extract PlantPart: seed Note: Patented) within Hepatoprotective Botanicals. Clinical nutrition protocols deploy this Pure Synergy formulation at ~$22.80/month for liver & hepatology support.

Typical: Standard Pure Synergy Superpure Milk Thistle capsule serving per NIH DSLD #246621 ~$23/mo
Hepatoprotective Botanicals DSLD #215911
Village Vitality Liver Detox with Milk Thistle 80%

Under NIH Dietary Supplement Label Database record #215911, Village Vitality Liver Detox with Milk Thistle 80% (capsule) combines Proprietary Blend, Oregon Grape, Yellow Dock (Proprietary Blend Note: herb weight equivalence) for targeted milk thistle repletion inside the Hepatoprotective Botanicals spectrum.

Typical: 1–2 capsules of Village Vitality Liver Detox with Milk Thistle 80% daily per DSLD #215911 panel ~$21/mo
Hepatoprotective Botanicals DSLD #262670
Wonder Laboratories Silymarin Milk Thistle

Verified against federal label #262670, Wonder Laboratories Silymarin Milk Thistle delivers Milk Thistle, Soybean Oil, Soy Lecithin (milk thistle (seed) (from 4:1 ext.) (equivalent to 1,000 mg milk thistle)) via softgel capsule dosing ($22.80/mo benchmark) to support hepatoprotective botanicals physiology.

Typical: Daily softgel capsule intake of Wonder Laboratories Silymarin Milk Thistle with food (Label #262670) ~$23/mo