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NIH Office of Dietary Supplements (DSLD v9) • Drug-Supplement Interactions

Dietary Supplements, Vitamins & Peptides (585)

Evidence-based guides to active ingredients, clinical trial dosages, prescription drug interactions (CYP450, bleeding, and absorption pathways), and anonymous patient micro-logs.

All Categories Neurotrophic B-Vitamins & Methylation (20) Essential Minerals & Electrolytes (17) Fat-Soluble Vitamins & Bone Health (17) Joint Cartilage & Mobility (16) Seasonal Immune Botanicals (16) Joint & Systemic Inflammation (10) Neuropathy & Glycemic Antioxidants (10) Cognitive Focus & Calm (10) Adaptogens & Stress Resilience (10) Mast-Cell, Allergy & Senolytic Flavonoids (10) Hepatoprotective Botanicals (9) NIH DSLD Cordyceps Formulations (9) NIH DSLD Manganese Formulations (9) Neuronal Membrane Phospholipids (9) NIH DSLD Copper Formulations (9) Mitochondrial & Cardiovascular (9) Sleep & Circadian Chronobiotics (9) NIH DSLD Boron Formulations (9) Stress & Autonomic Relaxation (9) Muscle, Longevity & Neuroenergetics (9) Cardiometabolic Lipids (9) Essential Minerals & Immune Defense (9) Microbiome & Gut Barrier (9) Polyphenols & Vascular Longevity (9) Thyroid & Prenatal Trace Minerals (9) Sleep Thermoregulation & Collagen Synthesis (8) NIH DSLD Molybdenum Formulations (8) NIH DSLD Betaine HCl Formulations (8) Serotonergic Precursors (Interaction Alert) (8) Joint & Mucosal 5-LOX Botanicals (8) Hematology & Oxygen Transport (8) Vascular Endothelial Amino Acids (8) Botanical Sleep Support (8) Urology & Prostate Health (8) PCOS, Fertility & Insulin Signaling (8) Cellular NAD+ & Mitochondrial Longevity (8) Cardiometabolic & Osmolyte Amino Acids (8) Cellular Detox & Redox (8) Dermatology, Tendon & Joint Matrix (8) Metabolic & Glycemic Botanicals (8) NIH DSLD Garlic Formulations (8) Ophthalmology & Macular Pigment (8) Thyroid & Redox Trace Minerals (8) Adaptogens & Mental Stamina (8) Collagen, Iron Uptake & Antioxidant (8) NIH DSLD Niacinamide Formulations (7) Vascular Endothelial & Exercise Performance (7) NIH DSLD Electrolytes Formulations (7) NIH DSLD Pantothenic Acid Formulations (7) NIH DSLD Beet Root Formulations (7) NIH DSLD Biotin Formulations (7) Cerebral Microcirculation & Tinnitus (7) Metabolic Trace Minerals (7) Vascular Calcification & Bone Matrix (7) NIH DSLD Vitamin A Formulations (7) Mitochondrial Fatty-Acid & Neuro-Support (7) Neurotrophic Medicinal Mushrooms (7) NIH DSLD Green Tea Extract Formulations (7) Mood Botanicals (High Interaction Alert) (6) NIH DSLD Cranberry Formulations (6) NIH DSLD Digestive Enzymes Formulations (6) Soluble Prebiotic Fiber & LDL Lowering (6) NIH DSLD Reishi Formulations (6) Antioxidants, Hepatic & Respiratory (6) NIH DSLD Hyaluronic Acid Formulations (5) NIH DSLD Vitamin B6 Formulations (5) NIH DSLD Vitamin E Formulations (5) Investigational Peptides & Tissue Repair (2) Endocrine & Visceral Adiposity Peptides (1) Bile Acids & Cholestatic Hepatoprotection (1) Sexual Health & Melanocortin Peptides (1) Dermal UV, Ocular & Lipid Carotenoids (1) TCA Cycle & Epigenetic Longevity (1) Mitochondrial Mitophagy & Longevity (1) Dermatology & Hair Peptides (1) Endocrine & Growth-Hormone Secretagogues (1) Nrf2 Cellular Detox & Antioxidant Defense (1) Autophagy & Cellular Longevity (1)
Mood Botanicals (High Interaction Alert) DSLD #8309
Bronson St. John's Wort

Formulated by Bronson (NIH DSLD #8309), Bronson St. John's Wort supplies St. John's Wort extract, Rice Flour (St. John's Wort extract (Form: standardized for 0.3% Hypericin) PlantPart: aerial part) as an oral capsule. Utilized across depression & mood regimens, typical monthly outlay averages $17.15.

Typical: Manufacturer-listed Bronson St. John's Wort capsule unit dose (#8309) ~$17/mo
Mood Botanicals (High Interaction Alert) DSLD #46629
Mrm St. John's Wort

Formulated by Mrm (NIH DSLD #46629), Mrm St. John's Wort supplies St. John’s Wort, Rice Flour (St. John’s Wort (Form: 0.3% Hypericins) Genus: Hypericum Species: perforatum) as an oral capsule. Utilized across depression & mood regimens, typical monthly outlay averages $15.57.

Typical: Manufacturer-listed Mrm St. John's Wort capsule unit dose (#46629) ~$16/mo
Mood Botanicals (High Interaction Alert) DSLD #208984
Plnt St. John's Wort

Under NIH Dietary Supplement Label Database record #208984, Plnt St. John's Wort (capsule) combines St. John's Wort extract, organic St. John’s Wort for targeted st johns wort repletion inside the Mood Botanicals (High Interaction Alert) spectrum.

Typical: 1–2 capsules of Plnt St. John's Wort daily per DSLD #208984 panel ~$20/mo
Mood Botanicals (High Interaction Alert) DSLD #224715
St. John's Wort Extract (Hypericum perforatum)

Standardized Hypericum perforatum extract clinically active in mild-to-moderate depression, carrying a critical clinical warning as one of the strongest botanical CYP3A4 and P-gp inducers.

Typical: 300 mg standardized extract (0.3% hypericin / 3% hyperforin) 3x daily ~$18/mo
Mood Botanicals (High Interaction Alert) DSLD #63587
Sundown Naturalist St. John's Wort 300 Mg

Under NIH Dietary Supplement Label Database record #63587, Sundown Naturalist St. John's Wort 300 Mg (capsule) combines St. John’s Wort extract for targeted st johns wort repletion inside the Mood Botanicals (High Interaction Alert) spectrum.

Typical: 1–2 capsules of Sundown Naturalist St. John's Wort 300 Mg daily per DSLD #63587 panel ~$22/mo
Mood Botanicals (High Interaction Alert) DSLD #30373
Sundown Naturals St. John's Wort

Sundown Naturals St. John's Wort (DSLD #30373) represents an on-market capsule preparation containing St. John’s Wort extract, Contains Less Than 2% of, evaluated in depression & mood and mood botanicals (high interaction alert) nutritional protocols.

Typical: Standard Sundown Naturals St. John's Wort capsule serving per NIH DSLD #30373 ~$19/mo