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Open Community Question @RedRockClimber_NV • 30-44F • 140 mg elemental Mg bisglyci • Week 8
▲ 33 Helpful • 2 Peer Replies

140 mg elemental Mg bisglycinate + 200 mg L-theanine (8 wks update): I had loose stools on a 'magnesium complex' that contained oxide, so I changed one thing at... — what worked for others here?

I had loose stools on a 'magnesium complex' that contained oxide, so I changed one thing at a time. First I switched to pure bisglycinate at 140 mg elemental, from 1,000 mg of compound, taken with dinner. Second, I added 200 mg L-theanine 45 minutes before bed after week 2. Third, I moved my iron tablet to the morning, 2+ hours away from magnesium. Stools were normal by day 4. Sleep onset improved from roughly 50 minutes to about 30 by week 8, though I still wake once most nights. It's not a cure, and it helped less on high-stress days. I also asked my doctor to check ferritin and B12 (ferritin 41 ng/mL, B12 about 510 pg/mL).

⚕ Pinned FDA / NIH / PubMed Clinical Context • Karim El-Sayed — Literature & Label Auditor

NIH ODS advises separating magnesium from certain drugs, including tetracycline and quinolone antibiotics and bisphosphonates, by at least 2 hours, and the label for your specific drug should be checked. Iron and divalent cations can compete for absorption, so spacing doses by about 2 hours is a common precaution.

Verified Peer Replies (2)

@PeachtreeRunner_GA • Verified Cohort Member • Week 12

Good method: you changed one variable at a time and tracked outcomes. Separating iron and magnesium by 2+ hours is a reasonable precaution. If you take levothyroxine, many labels advise 4 hours from mineral supplements. Check your own label and ask your pharmacist.

@ThyroidMorning_CA • Age 30-44 • Week 6

Same experience with oxide-containing blends. After I switched to a pure chelate and cut my dose to 120 mg elemental, the cramping stopped. I now keep a spreadsheet with product name, elemental mg, and stool changes.

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