dotMD.com
Cancer, Oncology & Supportive Care • ICD-10-CM C53.9

Cervical Cancer

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM C53.9 • 8 Linked .gov / PubMed Citations • Governance: Dr. Devon Caldwell, DO, MPH (NPI #1568063758)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Cervical Cancer Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

Ask our AI Specialists anything about Cervical Cancer

3 of 3 Free Questions Remaining

What Is Cervical Cancer?

What is cervical cancer? Cervical cancer is cancer that starts in the cells of the cervix. The cervix is part of the female reproductive system. It is the lower, narrow end of the uterus (womb), which opens into the vagina (birth canal). Cervical cancer usually develops slowly. Before cervical cells become cancer, they start to look abnormal. These cells are called "precancers." If they aren't destroyed or removed, they may become cancer cells that grow out of control and spread to other parts of your body. Screening tests for cervical cancer can help find abnormal cells so you can get treatment to prevent cervical cancer.

Pathophysiology, Underlying Causes & Clinical Presentation

Tissue-level etiology in Cervical Cancer (C53.9) features tumor-suppressor loss enabling in Cervical Cancer (C53.9: clonal proliferation). Cross-referenced with NIH MeSH (Uterine Cervical Neoplasms), therapeutic stabilization in cancer & oncology is verified against Comprehensive Metabolic & in Cervical Cancer (C53.9: Organ Function Panel).

Common Symptoms & Clinical Signs

  • • Have a weakened immune system because you: • Have a disease that harms your immune system, such as HIV
  • • Take medicine to control your immune system, such as certain medicines to treat cancer or autoimmune diseases
  • • Presentation of Cervical Cancer (C53.9): unintended weight loss [Cervical Cancer C53.9]
  • • Secondary Cervical Cancer clinical sign: unexplained bleeding, chronic in Cervical Cancer (C53.9: hoarseness/cough, or progressive)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Cervical Cancer Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code C53.9 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Cancer, Oncology & Supportive Care NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Complete Blood Count in Cervical Cancer (C53.9: (ANC, Hemoglobin, Platelets)) Safe hematologic reserve (C53.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Comprehensive Metabolic & in Cervical Cancer (C53.9: Organ Function Panel) Preserved renal/hepatic clearance (C53.9) Clinical Reference Target Range
Diagnostic / Lab Marker: Pathology / Molecular in Cervical Cancer (C53.9: Genomic Staging) Guideline-concordant surveillance (C53.9) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Cervical Cancer

Check Drug Interactions →
Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Dinoprostone Cervidil, Prepidil • RxCUI 597957 Prostaglandin Analog 93% $1.6400 $ 74.92 /mo
Cervidil (Dinoprostone) Cervidil • RxCUI 597959 Prostaglandin Analog 85% $0.2300 $ 25.06 /mo
Prepidil (Dinoprostone) Prepidil • RxCUI RXN-B00093359 Prostaglandin Analog 91% $0.7400 $ 61.78 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Cervical Cancer)

Browse All PubMed Translations →
Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Monofilament suture versus braided suture thread to improve pregnancy outcomes: What a 1,025-Participant Study Found

Monofilament suture did not reduce rate of pregnancy loss when compared with a braided suture.

Lancet (London, England) • 2022-10-22 • Phase III Randomized Trial
N = 1,025 90/100 PMID 36273481 ↗
Can This Approach Help? Inside the Latest Research on Benefits and safety of controlled-release dinoprostone vaginal delivery system

PROPESS administration for a maximum of 12 h was an effective and well-tolerated treatment for pregnant Japanese women post-term requiring cervical ripening.

The journal of obstetrics and gynaecology research • 2021-01-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 33094550 ↗
Can This Approach Help? Inside the Latest Research on Benefits and safety of DaxibotulinumtoxinA for injection in adults with cervical

This pooled analysis of two phase 3 trials demonstrates that DAXI is an effective, safe, and long-acting treatment for CD.

Parkinsonism & related disorders • 2025-11-15 • Phase III Randomized Trial
N = 149 88/100 PMID 40961718 ↗
Pembrolizumab with chemoradiotherapy followed by pembrolizumab for stage III-IVa cervical cancer: is the ENGOT-cx11/GOG-3047/KEYNOTE-A18 trial practice changing?

The associated costs render it unattainable in the regions where burden of cervical cancer is highest.

Cancer • 2025-02-15 • Phase III Randomized Trial
Multi-cohort 88/100 PMID 39913282 ↗
New Insights on Low-Dose-Rate versus High-Dose-Rate intracavitary brachytherapy in cervical: What a 441-Participant Study Found

HDR intracavitary brachytherapy with 7 Gy per fraction weekly is superior to LDR in terms of late rectal and bladder complications.

Brachytherapy • 2021-01-15 • Phase III Randomized Trial
N = 441 87/100 PMID 34598883 ↗
Zero-PHI Patient Support & Cohort Discussions

Cervical Cancer Patient Community & “People Like Me” Threads

“People Like Me” Cohort Filter (Zero-PHI)

Filter Cervical Cancer community threads and patient logs by age, biological sex, dosage, and treatment duration.

No threads match this cohort filter yet. Click + Start Anonymous Discussion to ask the community about Cervical Cancer.

Related Conditions in Cancer, Oncology & Supportive Care