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Type 1 & Type 2 Diabetes • ICD-10-CM E13.10

Diabetic ketoacidosis (DKA)

Also known as: Diabetic ketoacidosis, Diabetes, Diabetic

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM E13.10 • 8 Linked .gov / PubMed Citations • Governance: Dr. Elena Vance, MD, FACE (NPI #1043218901)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Diabetic ketoacidosis (DKA) Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Diabetic ketoacidosis (DKA)?

Clinical triage of Diabetic ketoacidosis (DKA) (also termed Diabetic ketoacidosis or Diabetes) (E13.10) in Diabetes & Glucose relies on hemoglobin A1c tracking [Diabetic ketoacidosis (DKA) E13.10], guiding step-wise therapeutic adjustments toward Hemoglobin A1c (HbA1c) [Diabetic ketoacidosis (DKA) E13.10] (4.8% – 5.6% (< 6.5% clinical target) (E13.10)).

Pathophysiology, Underlying Causes & Clinical Presentation

Diabetic ketoacidosis (DKA) (E13.10) alters diabetes & glucose homeostasis through renal SGLT2 glucose in Diabetic ketoacidosis (DKA) (E13.10: hyper-reabsorption); clinical remission targets Hemoglobin A1c (HbA1c) [Diabetic ketoacidosis (DKA) E13.10] within 4.8% – 5.6% (< 6.5% clinical target) (E13.10).

Common Symptoms & Clinical Signs

  • • Presentation of Diabetic ketoacidosis (DKA) (E13.10): blurred vision fluctuations in Diabetic ketoacidosis (DKA) (E13.10: or slower healing)
  • • Secondary Diabetic ketoacidosis (DKA) clinical sign: elevated fasting blood in Diabetic ketoacidosis (DKA) (E13.10: glucose or post-meal)
  • • Symptom flares in Diabetic ketoacidosis (DKA) correlating with CGM Time-in-Range (70–140 in Diabetic ketoacidosis (DKA) (E13.10: mg/dL)) deviation outside > 85% (E13.10)
  • • Functional diabetes & glucose impact requiring hemoglobin A1c tracking [Diabetic ketoacidosis (DKA) E13.10] evaluation (E13.10)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Diabetic ketoacidosis (DKA) Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code E13.10 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Type 1 & Type 2 Diabetes NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: CGM Time-in-Range (70–140 in Diabetic ketoacidosis (DKA) (E13.10: mg/dL)) > 85% (E13.10) Clinical Reference Target Range
Diagnostic / Lab Marker: Hemoglobin A1c (HbA1c) [Diabetic ketoacidosis (DKA) E13.10] 4.8% – 5.6% (< 6.5% clinical target) (E13.10) Clinical Reference Target Range
Diagnostic / Lab Marker: Fasting Plasma Glucose [Diabetic ketoacidosis (DKA) E13.10] 75 – 95 mg/dL (E13.10) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Diabetic ketoacidosis (DKA)

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Treatment selection for Diabetic ketoacidosis (DKA) depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Diabetic ketoacidosis (DKA))

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Real-world benefits and safety of liraglutide in the obese, non-diabetic: What a 4,754-Participant Study Found

This systematic review and meta-analysis indicates that liraglutide to be an effective and safe treatment for weight loss in the obese, non-diabetic individuals.

African health sciences • 2019-09-15 • Meta-Analysis
N = 4,754 99/100 PMID 32127832 ↗
New Insights on Weight Loss With GLP-1 Agonists in Nondiabetic Adults: Systematic Review and: What a 14,059-Participant Study Found

Tirzepatide, particularly at higher doses, provides the greatest weight reduction in adults without diabetes.

Obesity (Silver Spring, Md.) • 2026-06-15 • Meta-Analysis
N = 14,059 99/100 PMID 41936548 ↗
New Insights on Benefits and safety of anti-prediabetic drugs in patients with prediabetes: a: What a 16,610-Participant Study Found

Among all the included interventions, GLP-1RAs, GIP/GLP-1RAs, and TZDs demonstrated favorable anti-prediabetic efficacy and acceptable safety.

BMC medicine • 2026-02-19 • Meta-Analysis
N = 16,610 99/100 PMID 41715123 ↗
New Insights on A clinical trial in type 2 diabetic: What a 1,715-Participant Study Found

This large-scale international trial should help define the clinical course and standards of care for hypertensive adults with type 2.

American journal of kidney diseases : the official journal of the National Kidney Foundation • 2001-10-15 • Randomized Controlled Trial
N = 1,715 96/100 PMID 11576953 ↗
New Insights on Continuum of renoprotection with losartan at all stages of type 2 diabetic: What a 1,513-Participant Study Found

In proteinuric individuals with type 2 diabetes, losartan therapy reduced ESRD and hospitalizations for heart failure and was well tolerated at all levels of kidney function.

Journal of the American Society of Nephrology : JASN • 2004-12-15 • Randomized Controlled Trial
N = 1,513 96/100 PMID 15579515 ↗
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