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Cancer, Oncology & Supportive Care • ICD-10-CM C81.90

Hodgkin's lymphoma

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM C81.90 • 8 Linked .gov / PubMed Citations • Governance: Dr. Devon Caldwell, DO, MPH (NPI #1568063758)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Hodgkin's lymphoma Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Hodgkin's lymphoma?

Cataloged under federal diagnostic code C81.90 in Cancer & Oncology, Hodgkin's lymphoma requires immunohistochemistry [Hodgkin's lymphoma C81.90] so specialists can calibrate treatment intensity against Pathology / Molecular in Hodgkin's lymphoma (C81.90: Genomic Staging) benchmarks.

Pathophysiology, Underlying Causes & Clinical Presentation

Tissue-level etiology in Hodgkin's lymphoma (C81.90) features microenvironment inflammation [Hodgkin's lymphoma C81.90]. therapeutic stabilization in cancer & oncology is verified against Complete Blood Count in Hodgkin's lymphoma (C81.90: (ANC, Hemoglobin, Platelets)).

Common Symptoms & Clinical Signs

  • • Presentation of Hodgkin's lymphoma (C81.90): unexplained bleeding, chronic in Hodgkin's lymphoma (C81.90: hoarseness/cough, or progressive)
  • • Secondary Hodgkin's lymphoma clinical sign: abnormality detected early in Hodgkin's lymphoma (C81.90: on age-appropriate screening)
  • • Symptom flares in Hodgkin's lymphoma correlating with Pathology / Molecular in Hodgkin's lymphoma (C81.90: Genomic Staging) deviation outside Guideline-concordant surveillance (C81.90)
  • • Functional cancer & oncology impact requiring immunohistochemistry [Hodgkin's lymphoma C81.90] evaluation (C81.90)

Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗

Hodgkin's lymphoma Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code C81.90 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Cancer, Oncology & Supportive Care NIH MedlinePlus Health Topics
Diagnostic / Lab Marker: Pathology / Molecular in Hodgkin's lymphoma (C81.90: Genomic Staging) Guideline-concordant surveillance (C81.90) Clinical Reference Target Range
Diagnostic / Lab Marker: Complete Blood Count in Hodgkin's lymphoma (C81.90: (ANC, Hemoglobin, Platelets)) Safe hematologic reserve (C81.90) Clinical Reference Target Range
Diagnostic / Lab Marker: Comprehensive Metabolic & in Hodgkin's lymphoma (C81.90: Organ Function Panel) Preserved renal/hepatic clearance (C81.90) Clinical Reference Target Range
Marcus Sterling (AI Healthcare Price Auditor) & Dr. Vance

FDA-Monographed Medications & Public Cash Price Reference for Hodgkin's lymphoma

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Medication Pharmacologic Class Patient Worth-It CMS NADAC / Unit Typical Lowest Cash
Gallium Citrate Ga-67 Gallium Citrate Ga-67 Generic • RxCUI RXN-69945180-1786 FDA Prescription Therapeutic Agent 89% $0.5500 $ 30.78 /mo
Dr. Lin (AI PubMed Clinical Trial Lead)

Peer-Reviewed Human Clinical Trials & Meta-Analyses (Hodgkin's lymphoma)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Daily Oral Ibandronate With Adjuvant Endocrine Therapy in Postmenopausal Women: What a 1,116-Participant Study Found

In postmenopausal women with ER+ breast cancer, adjuvant ibandronate 50 mg once daily does not improve DFS and should not be recommended as part of standard treatment regimens.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2022-09-01 • Phase III Randomized Trial
N = 1,116 90/100 PMID 35442755 ↗
Can This Approach Help? Inside the Latest Research on A Phase 1/2 Study of CAT-8015 in Adult Relapsed or Refractory B-Cell Non-Hodgkin

The primary objectives of this study are to determine the maximum tolerated dose (MTD) or optimal biologic dose (OBD) and safety profile of CAT-8015 in participants with relapsed or refractory advanced B-cell NHL (diffuse large B-cell lymph

ClinicalTrials.gov Registry (NIH NLM) • 2013-03-04 • Completed Human Clinical Trial (NCT)
N = 23 89/100 PMID NCT01030536 ↗
Can This Approach Help? Inside the Latest Research on Lenalidomide Plus Rituximab for Relapsed/Refractory Indolent Non-Hodgkin

Improved long-term efficacy with R 2 versus R-placebo and manageable safety with R 2 were observed in patients with FL, including those 70 years and older.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2026-06-15 • Phase III Randomized Trial
N = 66 88/100 PMID 41990300 ↗
Managing Sarcomatoid kidney cell carcinoma: Can Add-on treatment Make a Real Difference? (What a 171-Person Study Found)

Add-on treatment with sunitinib or sorafenib did not show an improvement in DFS or OS in patients with sRCC.

BJU international • 2022-06-15 • Phase III Randomized Trial
N = 171 88/100 PMID 34480522 ↗
New Insights on High-Dose Once-Daily Thoracic Radiotherapy in Limited-Stage Small-Cell Lung: What a 313-Participant Study Found

Although 45-Gy twice-daily radiotherapy remains the standard of care, this study provides the most robust information available to help guide the choice of thoracic radiotherapy regimen for patients with limited-stage...

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2023-05-01 • Phase III Randomized Trial
N = 313 87/100 PMID 36623230 ↗
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Hodgkin's lymphoma Patient Community & “People Like Me” Threads

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