Potassium
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Potassium Key Takeaways
Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level
- 1 What it does: Potassium is a mineral that your body needs to work properly.
- 2 Real-world patient consensus: Mapped to Chronic Kidney Disease & Electrolytes under ICD-10-CM E87.5 for Potassium clinical workups.
- 3 Typical cash cost range: Differential triage of Potassium (E87.5) utilizes NSAID/nephrotoxin avoidance [Potassium E87.5].
- 4 Top reported side effects / signs: Objective lab/clinical target for Potassium: eGFR (Creatinine + in Potassium (E87.5: Cystatin C)) (>= 90 mL/min/1.73m2 (E87.5)) and Urine Albumin-to-Creatinine Ratio in Potassium (E87.5: (uACR)).
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What Is Potassium?
Potassium is a mineral that your body needs to work properly. It is a type of electrolyte . It helps your nerves to function and muscles to contract. It helps your heartbeat stay regular. It also helps move nutrients into cells and waste products out of cells. A diet rich in potassium helps to offset some of sodium's harmful effects on blood pressure. Many people get all the potassium they need from what they eat and drink.
Pathophysiology, Underlying Causes & Clinical Presentation
Pathophysiologically, Potassium (ICD-10 E87.5) is driven by intrarenal RAAS activation [Potassium E87.5]; Cross-referenced with NIH MeSH (Potassium, Dietary, Potassium), specialists in Chronic Kidney Disease & Electrolytes monitor Urine Albumin-to-Creatinine Ratio in Potassium (E87.5: (uACR)) to gauge tissue recovery.
Common Symptoms & Clinical Signs
- • Leafy greens, such as spinach and collards
- • Fruit from vines, such as grapes and blackberries
- • Presentation of Potassium (E87.5): fatigue, muscle cramps, in Potassium (E87.5: metallic taste, or)
- • Secondary Potassium clinical sign: changes in urine in Potassium (E87.5: output volume, nocturnal)
Primary Federal Reference: NIH / National Library of Medicine MedlinePlus Entry ↗
Potassium Diagnostic Classification & Lab Markers
| Metric | Verified Benchmark | Source |
|---|---|---|
| ICD-10-CM Diagnostic Code | E87.5 | WHO / CMS ICD-10-CM Clinical Classification |
| Clinical Specialty Hub | Chronic Kidney Disease & Electrolytes | NIH MedlinePlus Health Topics |
| Diagnostic / Lab Marker: eGFR (Creatinine + in Potassium (E87.5: Cystatin C)) | >= 90 mL/min/1.73m2 (E87.5) | Clinical Reference Target Range |
| Diagnostic / Lab Marker: Urine Albumin-to-Creatinine Ratio in Potassium (E87.5: (uACR)) | < 15 mg/g (< 30 mg/g normal) (E87.5) | Clinical Reference Target Range |
| Diagnostic / Lab Marker: Serum Potassium, Bicarbonate in Potassium (E87.5: & Phosphorus) | K+ 3.8–4.8 mEq/L; HCO3 23–29 mEq/L (E87.5) | Clinical Reference Target Range |
FDA-Monographed Medications & Public Cash Price Reference for Potassium
| Medication | Pharmacologic Class | Patient Worth-It | CMS NADAC / Unit | Typical Lowest Cash |
|---|---|---|---|---|
| Potassium Phosphates (Potassium Phosphate, Monobasic Potassium Phosphate, Dibasic) Potassium Phosphates • RxCUI 1928569 | Osmotic Laxative | 79% | $2.3400 | $ 176.98 /mo |
| Potassium Iodide Iosat, Sski • RxCUI 312541 | FDA Prescription Therapeutic Agent | 93% | $0.5900 | $ 32.39 /mo |
| Diclofenac Potassium 25 Mg Diclofenac Potassium 25 Mg Generic • RxCUI RXN-59088131-2542 | Nonsteroidal Anti-inflammatory Drug | 90% | $2.6951 | $ 117.65 /mo |
| Klor-Con (Potassium Chloride) Klor-Con • RxCUI 628953 | Osmotic Laxative | 89% | $0.1181 | $ 13.51 /mo |
| Urocit-K (Potassium Citrate) Urocit-K • RxCUI 199381-B01780615 | Anti-coagulant | 85% | $1.8600 | $ 7.21 /mo |
| Pylera (Bismuth Subcitrate Potassium, Metronidazole, and Tetracycline Hydrochloride) Pylera • RxCUI 1294619-B61269381 | Nitroimidazole Antimicrobial | 75% | $2.4278 | $ 91.54 /mo |
| Augmentin Es-600 (Amoxicillin and Clavulanate Potassium) Augmentin Es-600 • RxCUI RXN-B81964003 | Penicillin-class Antibacterial | 87% | $0.0179 | $ 9.79 /mo |
| Pokonza (Potassium Chloride) Pokonza • RxCUI 1867544-B15370306 | Osmotic Laxative | 83% | $27.4582 | $ 640.00 /mo |
| Klor-Con/Ef (Potassium Bicarbonate) Klor-Con/Ef • RxCUI RXN-B02455326 | Osmotic Laxative | 94% | $0.8594 | $ 70.38 /mo |
| Potassium Phosphate Potassium Phosphate Generic • RxCUI RXN-70069746-3119 | Osmotic Laxative | 90% | $0.7500 | $ 38.88 /mo |
| Potassium Chloride and Dextrose Monohydrate Potassium Chloride in Dextrose • RxCUI RXN-03380683-3111 | Osmotic Laxative | 92% | $0.1900 | $ 16.20 /mo |
| Iosat (Potassium Iodide) Iosat • RxCUI 430174 | Over-the-Counter Clinical Monograph | 86% | $3.3000 | $ 246.10 /mo |
| Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride Pylera • RxCUI 1294619 | Nitroimidazole Antimicrobial | 81% | $2.4278 | $ 106.82 /mo |
| Amifampridine Phosphate Firdapse • RxCUI RXN-69616211-3117 | Potassium Channel Blocker | 86% | $0.3800 | $ 23.89 /mo |
| Pfizerpen (Penicillin G Potassium) Pfizerpen • RxCUI 995906 | Penicillin-class Antibacterial | 74% | $0.0442 | $ 11.68 /mo |
| Veltassa (Patiromer) Veltassa • RxCUI 1716215 | Potassium Binder | 87% | $34.0169 | $ 640.00 /mo |
Peer-Reviewed Human Clinical Trials & Meta-Analyses (Potassium)
| Study & Plain-English Finding | Sample (N) | Rigor | Primary Source |
|---|---|---|---|
| New Insights on Fixed-dose Combinations of Amlodipine/Losartan Potassium/Chlorthalidone and: What a 328-Participant Study Found Of 330 patients from 33 medical centers, 328 patients who had available efficacy data were analyzed. Clinical therapeutics • 2017-10-15 • Phase III Randomized Trial | N = 328 | 93/100 | PMID 28939406 ↗ |
| New Insights on Magnesium and potassium supplementation on trouble sleeping and sleep hormones in: What a 320-Participant Study Found The study revealed that magnesium, potassium, and magnesium and potassium combined had a significant effect on serum cortisol and melatonin levels (sleep hormones). Frontiers in endocrinology • 2024-01-15 • Randomized Controlled Trial | N = 320 | 93/100 | PMID 39534260 ↗ |
| Can This Approach Help? Inside the Latest Research on Tolvaptan how the body absorbs the medicine and how the medicine works in the Tolvaptan was associated with large increases in free water clearance and urine output. European journal of pediatrics • 2025-12-18 • Phase III Randomized Trial | Multi-cohort | 88/100 | PMID 41407907 ↗ |
| Can This Approach Help? Inside the Latest Research on Reduction in the magnitude of serum potassium elevation in combination therapy In Japanese patients with type 2 diabetes and albuminuria treated with esaxerenone, concomitant use of SGLT2 inhibitor reduced the magnitude of serum potassium elevation without any change of its blood-pressure-lowering and... Journal of diabetes investigation • 2022-07-15 • Phase III Randomized Trial | Multi-cohort | 88/100 | PMID 35199478 ↗ |
| Can This Approach Help? Inside the Latest Research on Effect of Food on the how the body absorbs the medicine, how the medicine works This flexibility may enhance its clinical utility as an acid-suppressive therapy. Clinical and translational science • 2026-11-15 • Randomized Controlled Trial | Multi-cohort | 82/100 | PMID 42963322 ↗ |
Potassium Patient Community & “People Like Me” Threads
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