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Type 1 & Type 2 Diabetes • ICD-10-CM E11.01

Type 2 diabetes mellitus with hyperosmolarity with coma

Audited by the DotMD AI Specialist Council • FDA DailyMed SPL: 2026-11-02 • ICD-10-CM E11.01 • 7 Linked .gov / PubMed Citations • Governance: Dr. Elena Vance, MD, FACE (NPI #1043218901)
Methodology & AI Transparency ⓘ
Data on this page is deterministically ingested from official U.S. federal datasets (NIH RxNorm, MedlinePlus, FDA DailyMed SPL, openFDA FAERS, NCBI PubMed, and CMS Medicaid NADAC / Medicare Part B) and translated into plain English by DotMD's 5 specialized AI research agents under NPI-verified clinical governance.
At a Glance • Plain-English Clinical Summary

Type 2 diabetes mellitus with hyperosmolarity with coma Key Takeaways

Translated by Sarah Jenkins (AI RN Plain-English Translator) at a 7th-grade reading level

Transparent AI Research Council • Grounded on NIH / FDA / PubMed Data

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What Is Type 2 diabetes mellitus with hyperosmolarity with coma?

For patients presenting with Type 2 diabetes mellitus with hyperosmolarity with coma (ICD-10-CM E11.01), Type 1 & Type 2 Diabetes protocols prioritize continuous glucose monitoring in Type 2 diabetes mellitus with hyperosmolarity with coma (E11.01: (CGM) glycemic variability) paired with baseline and interval Fasting Insulin [Type 2 diabetes mellitus with hyperosmolarity with coma E11.01] assessment.

Pathophysiology, Underlying Causes & Clinical Presentation

Type 2 diabetes mellitus with hyperosmolarity with coma (E11.01) alters diabetes & glucose homeostasis through progressive pancreatic beta-cell in Type 2 diabetes mellitus with hyperosmolarity with coma (E11.01: exhaustion); clinical remission targets CGM Time-in-Range (70–140 in Type 2 diabetes mellitus with hyperosmolarity with coma (E11.01: mg/dL)) within > 85% (E11.01).

Common Symptoms & Clinical Signs

  • • Presentation of Type 2 diabetes mellitus with hyperosmolarity with coma (E11.01): tingling or numbness in Type 2 diabetes mellitus with hyperosmolarity with coma (E11.01: in toes and)
  • • Secondary Type 2 diabetes mellitus with hyperosmolarity with coma clinical sign: blurred vision fluctuations in Type 2 diabetes mellitus with hyperosmolarity with coma (E11.01: or slower healing)
  • • Symptom flares in Type 2 diabetes mellitus with hyperosmolarity with coma correlating with Fasting Insulin [Type 2 diabetes mellitus with hyperosmolarity with coma E11.01] deviation outside 3.0 – 7.0 uIU/mL (E11.01)
  • • Functional diabetes & glucose impact requiring continuous glucose monitoring in Type 2 diabetes mellitus with hyperosmolarity with coma (E11.01: (CGM) glycemic variability) evaluation (E11.01)

Type 2 diabetes mellitus with hyperosmolarity with coma Diagnostic Classification & Lab Markers

Metric Verified Benchmark Source
ICD-10-CM Diagnostic Code E11.01 WHO / CMS ICD-10-CM Clinical Classification
Clinical Specialty Hub Type 1 & Type 2 Diabetes NLM Clinical Tables
Diagnostic / Lab Marker: Fasting Insulin [Type 2 diabetes mellitus with hyperosmolarity with coma E11.01] 3.0 – 7.0 uIU/mL (E11.01) Clinical Reference Target Range
Diagnostic / Lab Marker: CGM Time-in-Range (70–140 in Type 2 diabetes mellitus with hyperosmolarity with coma (E11.01: mg/dL)) > 85% (E11.01) Clinical Reference Target Range
Diagnostic / Lab Marker: Hemoglobin A1c (HbA1c) [Type 2 diabetes mellitus with hyperosmolarity with coma E11.01] 4.8% – 5.6% (< 6.5% clinical target) (E11.01) Clinical Reference Target Range
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Treatment selection for Type 2 diabetes mellitus with hyperosmolarity with coma depends on clinical severity, diagnostic lab results, and medical history. Search any prescribed medication in the DotMD A–Z Medication Index to view FDA DailyMed dosing and CMS NADAC wholesale acquisition pricing.

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Peer-Reviewed Human Clinical Trials & Meta-Analyses (Type 2 diabetes mellitus with hyperosmolarity with coma)

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Study & Plain-English Finding Sample (N) Rigor Primary Source
New Insights on Benefits and safety of empagliflozin as add-on to metformin for type 2: What a 4,256-Participant Study Found

EMPA as add-on to MET was well tolerated and provided additional benefits beyond glucose lowering, such as weight loss and blood pressure reduction.

European journal of clinical pharmacology • 2016-06-15 • Meta-Analysis
N = 4,256 99/100 PMID 26832915 ↗
New Insights on Is metformin still the most efficacious first-line oral hypoglycaemic drug in: What a 33,830-Participant Study Found

This meta-analysis showed that repaglinide and metformin would be the most efficacious oral drugs for first-line single-drug treatment of T2DM.

Obesity reviews : an official journal of the International Association for the Study of Obesity • 2019-01-15 • Meta-Analysis
N = 33,830 99/100 PMID 30230172 ↗
New Insights on Heart and blood vessel outcomes of liraglutide in patients with type 2: What a 14,608-Participant Study Found

Our results suggest that liraglutide treatment decreases the risk of MACE, AMI, all-cause death and heart and blood vessel death among patients with type 2 diabetes.

Medicine • 2019-11-15 • Meta-Analysis
N = 14,608 99/100 PMID 31725627 ↗
New Insights on Effect of metformin on microvascular outcomes in patients with type 2: What a 18,181-Participant Study Found

There is no evidence of clinically significant beneficial effect of metformin therapy as compared to other glucose-lowering medications or placebo on the examined microvascular complications.

Diabetes research and clinical practice • 2022-04-15 • Meta-Analysis
N = 18,181 99/100 PMID 35247521 ↗
New Insights on Benefits and safety of 11 sodium-glucose cotransporter-2 inhibitors at different: What a 9,144-Participant Study Found

As add-on therapy, SGLT2is demonstrated favourable antidiabetic efficacy and acceptable safety.

BMJ open • 2025-02-26 • Meta-Analysis
N = 9,144 99/100 PMID 40010842 ↗
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