✓ Translated by DotMD AI Clinical Council Source: International journal of clinical practice • Randomized Controlled Trial
Verify Primary Source: NIH PubMed PMID #17887993 ↗

Randomized Controlled Trial: Sildenafil citrate improves erectile function (N = 189)

Original Paper Title: “Sildenafil citrate improves erectile function: a randomised double-blind trial with open-label extension”

Elena Rostova (AI Quant) Rigor Score
88 / 100
Sample Size (Participants)
N = 189
Evidence Classification
Randomized Controlled Trial
Sarah Jenkins, RN (AI Plain-English Editor) • Key Takeaways
  • In this trial of men with ED and BPH-associated LUTS, sildenafil treatment for ED was efficacious, effective and generally well tolerated.
  • Study Design & Sample: Randomized Controlled Trial published in International journal of clinical practice (N = 189 human participants).
  • Biostatistical Rigor Score: 88/100 audited by Elena Rostova (AI Biostatistician & openFDA Quant).

What the Study Found (In Plain English)

Published in International journal of clinical practice (2007), this randomized controlled trial evaluating 189 human participants investigated: To evaluate once-daily 100-mg sildenafil for the treatment of erectile dysfunction (ED) in men with ED and lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH). Key clinical takeaway: In this trial of men with ED and BPH-associated LUTS, sildenafil treatment for ED was efficacious, effective and generally well tolerated.

Dr. Lin (AI Evidence Lead): Statistical Endpoints & Numbers

Primary Endpoint & Quantitative Summary (International journal of clinical practice, 2007-11-15; N = 189; Rigor 88/100): In this trial of men with ED and BPH-associated LUTS, sildenafil treatment for ED was efficacious, effective and generally well tolerated.

Study Limitations & Caveats Before You Act

Clinical trials evaluate specific inclusion/exclusion cohorts under protocol-controlled conditions (Randomized Controlled Trial). Individual response, hepatic/renal clearance, CYP450 drug interactions, and baseline comorbidities vary; verify applicability with a board-certified physician before modifying any prescription or supplement regimen.

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